Press and media

The results of the SOLUS Project will have a significant impact on breast cancer diagnosis and treatment. As a result, keeping all stakeholders informed and up-to-date is also a key aim of the project and a range of press and dissemination material will be created at each stage of the project to announce the latest results.

SOLUS Videos

We have published two videos about the project. The first video is a short explainer of the project's overall objective and a summary of our overall results, and the impact these have.


The second video is a more in-depth demonstration of the SOLUS system's operation, in addition to information about the project, it's objectives and the scientific need.


Name Date File
Smart Optode Rollup 2019-10-14 07:47:15 SOLUS smart optode rollup.jpg
HealthManagement.org review article 2019-02-13 07:49:02 HM_v19_i1-Paola Taroni- A multimodel sysytem for the diagnosis of breast cancer the SOLUS project.pdf
Diagnostic Imaging Europe review article 2018-06-28 12:23:26 SOLUS-DIEurope-MayJune-2018.pdf
SOLUS in ECR Today 2018 2018-03-01 12:45:54 ECR Today 2018_Thursday_March 1.pdf
SOLUS general information rollup 2018-02-26 12:35:13 SOLUS rollup 2018 - print.pdf
SOLUS general information folder 2018-02-26 12:34:45 SOLUS folder 2018 - print.pdf
Public launch press release 2017-02-28 22:21:30 SOLUS Press Release 1 - Innovation in the diagnosis of breast cancer.pdf

Publications

During the course of it's four-year research period, SOLUS researchers will publish scientific articles and every effort will be made to make these available on an open-access basis.

Below is a list of publications related to the SOLUS Project which will be updated as the project progresses.

Title

Authors

Journal

DOI/link

Non-invasive optical estimate of tissue composition to differentiate malignant from benign breast lesions: A pilot study

Paola Taroni, Anna Maria Paganoni, Francesca Ieva, Antonio Pifferi, Giovanna Quarto, Francesca Abbate, Enrico Cassano, Rinaldo Cubeddu

Scientific Reports

10.1038/srep40683

Chromophore decomposition in multispectral time-resolved diffuse optical tomography

Judy Zouaoui, Laura Di Sieno, Lionel Hervé, Antonio Pifferi, Andrea Farina, Alberto Dalla Mora, Jacques Derouard, Jean-Marc Dinten

Biomedical Optics Express

10.1364/BOE.8.004772

Time-domain diffuse optical tomography using silicon photomultipliers: feasibility study

Laura Di Sieno, Judy Zouaoui, Lionel Hervé, Antonio Pifferi, Andrea Farina, Edoardo Martinenghi, Jacques Derouard, Jean-Marc Dinten, Alberto Dalla Mora

Journal of Biomedical Optics

10.1117/1.JBO.21.11.116002

High throughput detection chain for time domain optical mammography

Edoardo Ferocino, Edoardo Martinenghi, Alberto Dalla Mora, Antonio Pifferi, Rinaldo Cubeddu, Paola Taroni

Biomedical Optics Express

10.1364/boe.9.000755

Attractive new technologies for 7-wavelength time domain optical mammography

Edoardo Ferocino, Edoardo Martinenghi, Alberto Dalla Mora, Antonio Pifferi, Rinaldo Cubeddu, Paola Taroni

Diffuse Optical Spectroscopy and Imaging VI

10.1117/12.2286058

Performance evaluation of time-domain multispectral diffuse optical tomography in the reflection geometry

Lionel Hervé, Judy Zouaoui, David Orive-Miguel, Laura Di Sieno, Antonio Pifferi, Andrea Farina, Alberto Dalla Mora, Jacques Derouard, Jérôme Mars, Laurent Condat, Jean-Marc Dinten

Diffuse Optical Spectroscopy and Imaging VI

10.1117/12.2285811

Gating techniques for InGaAs/InP and silicon SPADs

Alberto Tosi, Mirko Sanzaro, Mauro Buttafava, Alessandro Ruggeri,
Enrico Conca, Marco Renna, Federica Villa, Franco Zappa

Single Photon Workshop 2017

https://www.nist.gov/file/377316

Novel Approaches to Photon Detection and Timing for 7-Wavelength Time Domain Optical Mammography

E. Ferocino, E. Martinenghi, A. Dalla Mora, A. Pifferi, R. Cubeddu, P. Taroni

19th Italian National Conference on Photonic Technologies (Fotonica 2017)

10.1049/cp.2017.0204

How Should the New Generation of Detectors for Diffuse Optics Be? A Systematic Simulation Study

Laura Di Sieno, Anurag Behera, Antonio Pifferi, Fabrizio Martelli, Alberto Dalla Mora

Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS)

10.1364/translational.2018.jw3a.30

Novel Technologies for Time-Domain Diffuse Optics: Miniaturized Wearable Devices and Bioresorbable Optical Fibers

Alberto Dalla Mora, Laura Di Sieno, Sanathana Konugolu Venkata Sekar, Andrea Farina, Davide Contini, Nadia G. Boetti, Daniel Milanese, Jan Nissinen, Antonio Pifferi

Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS)

10.1364/ots.2018.of2d.6

Advances in Single-Photon Detection and Timing for Time Domain Multi-Wavelength Optical Mammography

Edoardo Ferocino, Edoardo Martinenghi, Alberto Dalla Mora, Antonio Pifferi, Rinaldo Cubeddu, Paola Taroni

Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS)

10.1364/translational.2018.jw3a.43

Instrumental, optical and geometrical parameters affecting time-gated diffuse optical measurements: a systematic study

Anurag Behera, Laura Di Sieno, Antonio Pifferi, Fabrizio Martelli, Alberto Dalla Mora

Biomedical Optics Express

10.1364/boe.9.005524

Systematic study of the effect of ultrasound gel on the performances of time-domain diffuse optics and diffuse correlation spectroscopy

Laura Di Sieno, Davide Contini, Giuseppe Lo Presti, Lorenzo Cortese, Tony Mateo, Bogdan Rosinski, Elena Venturini, Pietro Panizza, Mireia Mora, Gloria Aranda, Mattia Squarcia, Andrea Farina, Turgut Durduran, Paola Taroni, Antonio Pifferi, Alberto Dalla Mora

Biomedical Optics Express

10.1364/boe.10.003899

Multi Simulation Platform for Time Domain Diffuse Optical Tomography: An Application to a Compact Hand-Held Reflectance Probe

Edoardo Ferocino, Antonio Pifferi, Simon Arridge, Fabrizio Martelli, Paola Taroni, Andrea Farina

Applied Sciences

10.3390/app9142849

Multi-wavelength time domain diffuse optical tomography for breast cancer: initial results on silicone phantoms

Edoardo Ferocino, Giuseppe Di Sciacca, Laura Di Sieno, Alberto Dalla Mora, Antonio Pifferi, Simon R. Arridge, Fabrizio Martelli, Paola Taroni, Andrea Farina

Optical Tomography and Spectroscopy of Tissue XIII

10.1117/12.2508657

Solid heterogeneous phantoms for multimodal ultrasound and diffuse optical imaging: an outcome of the SOLUS project for standardization

Laura Di Sieno, Rinaldo Cubeddu, Hélène Sportouche, David Savéry, Sanathana Konugolu Venkata Sekar, Bogdan Rosinski, Andrea Farina, Edoardo Ferocino, Pranav Lanka, Paola Taroni, Antonio Pifferi, Alberto Dalla Mora

Novel Biophotonics Techniques and Applications V

10.1117/12.2526645

Effects of ultrasound impedance matching fluids on diffuse optical measurements

Laura Di Sieno, Davide Contini, Giuseppe Lo Presti, Lorenzo Cortese, Tony Mateo, Bogdan Rosinski, Elena Venturini, Pietro Panizza, Mireia Mora, Gloria Aranda, Mattia Squarcia, Andrea Farina, Turgut Durduran, Paola Taroni, Antonio Pifferi, Alberto Dalla Mora

Diffuse Optical Spectroscopy and Imaging VII

10.1117/12.2526925

Spectral approach to time domain diffuse optical tomography for breast cancer: validation on meat phantoms

Edoardo Ferocino, Giuseppe Di Sciacca, Laura Di Sieno, Alberto Dalla Mora, Antonio Pifferi, Simon Arridge, Fabrizio Martelli, Paola Taroni, Andrea Farina

Diffuse Optical Spectroscopy and Imaging VII

10.1117/12.2526649

Fitting a spectral model for component analysis in diffuse optical tomography

Giuseppe Di Sciacca, Edoardo Ferocino, Andrea Farina, Antonio Pifferi, Paola Taroni, Simon Arridge

Diffuse Optical Spectroscopy and Imaging VII

10.1117/12.2527119

Large area SiPM and high throughput timing electronics: toward new generation time-domain instruments

Anurag Behera, Laura Di Sieno, Sumeet Rohilla, Antonio Pifferi, Alessandro Torricelli, Davide Contini, Benedikt Kraemer, Felix Koberling, Alberto Dalla Mora

Diffuse Optical Spectroscopy and Imaging VII

10.1117/12.2526792

A Tool for Quantitative and Systematic Simulation of Diffuse Optical Tomography with a Limited Number of Fixed Sources and Detectors

Edoardo Ferocino, Antonio Pifferi, Simon Arridge, Fabrizio Martelli, Paola Taroni, Andrea Farina

Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS)

10.1364/translational.2018.jtu3a.25

Study of optimal measurement conditions for time-domain diffuse optics systems

Anurag Behera, Laura Di Sieno, Antonio Pifferi, Fabrizio Martelli, Alberto Dalla Mora

Biophotonics: Photonic Solutions for Better Health Care VI

10.1117/12.2307370

The SiPM revolution in time-domain diffuse optics

Alberto Dalla Mora, Laura Di Sieno, Anurag Behera, Paola Taroni, Davide Contini, Alessandro Torricelli, Antonio Pifferi

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

10.1016/j.nima.2020.164411

Probe-hosted large area silicon photomultiplier and high-throughput timing electronics for enhanced performance time-domain functional near-infrared spectroscopy

L. Di Sieno, A. Behera, S. Rohilla, E. Ferocino, D. Contini, A. Torricelli, B. Krämer, F. Koberling, A. Pifferi, A. Dalla Mora

Biomedical Optics Express

10.1364/boe.400868

Time-Gated Single-Photon Detection in Time-Domain Diffuse Optics: A Review

Alberto Dalla Mora, Laura Di Sieno, Rebecca Re, Antonio Pifferi, Davide Contini

Applied Sciences

10.3390/app10031101

SOLUS Project: Bringing Innovation into Breast Cancer Diagnosis and in the Time-Domain Diffuse Optical Field

Laura Di Sieno, Alberto Dalla Mora, Edoardo Ferocino, Antonio Pifferi, Alberto Tosi, Enrico Conca, Vincenzo Sesta, Andrea Giudice, Alessandro Ruggeri, Simone Tisa, Alexander Flocke, Bogdan Rosinski, Jean-Marc Dinten, Mathieu Perriollat, David Savery, Hélène Sportouche, Simon Arridge, Andrea Farina, Pietro Panizza, Elena Venturini, Peter Gordebeke, Pamela Zolda, Paola Taroni

Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN)

10.1364/ots.2020.stu1d.5

Broadband Time Domain Diffuse Optical Reflectance Spectroscopy: A Review of Systems, Methods, and Applications

Sanathana Konugolu Venkata Sekar, Pranav Lanka, Andrea Farina, Alberto Dalla Mora, Stefan Andersson-Engels, Paola Taroni, Antonio Pifferi

Applied Sciences

10.3390/app9245465

Large-Area, Fast-Gated Digital SiPM With Integrated TDC for Portable and Wearable Time-Domain NIRS

Enrico Conca, Vincenzo Sesta, Mauro Buttafava, Federica Villa, Laura Di Sieno, Alberto Dalla Mora, Davide Contini, Paola Taroni, Alessandro Torricelli, Antonio Pifferi, Franco Zappa, Alberto Tosi

IEEE Journal of Solid-State Circuits

10.1109/jssc.2020.3006442

Enhanced diffuse optical tomographic reconstruction using concurrent ultrasound information

G. Di Sciacca, L. Di Sieno, A. Farina, P. Lanka, E. Venturini, P. Panizza, A. Dalla Mora, A. Pifferi, P. Taroni, S. R. Arridge

Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences

10.1098/rsta.2020.0195

SPAD-based asynchronous-readout array detectors for image-scanning microscopy

Mauro Buttafava, Federica Villa, Marco Castello, Giorgio Tortarolo, Enrico Conca, Mirko Sanzaro, Simonluca Piazza, Paolo Bianchini, Alberto Diaspro, Franco Zappa, Giuseppe Vicidomini, Alberto Tosi

Optica

10.1364/optica.391726

Time-domain diffuse optics with 86  mm2 fast-gated SiPM for extreme light harvesting

L. Di Sieno, E. Ferocino, E. Conca, V. Sesta, M. Buttafava, F. Villa, F. Zappa, D. Contini, A. Torricelli, P. Taroni, A. Tosi, A. Pifferi, A. Dalla Mora

Optics Letters

10.1364/ol.413577

In vivo test-driven upgrade of a time domain multi-wavelength optical mammograph

Giulia Maffeis, Edoardo Ferocino, Alberto Dalla Mora, Antonio Pifferi, Rinaldo Cubeddu, Paola Taroni

Biomedical Optics Express

10.1364/boe.412210

SOLUS: an innovative multimodal imaging system to improve breast cancer diagnosis through diffuse optics and ultrasounds

Antonio Pifferi, Alberto Dalla Mora, Laura Di Sieno, Edoardo Ferocino, Alberto Tosi, Enrico Conca, Vincenzo Sesta, Andrea Giudice, Alessandro Ruggeri, Simone Tisa, Alexander Flocke, Bogdan Rosinski, Jean-Marc Dinten, Mathieu Perriollat, Christophe Fraschini, Hélène Sportouche, Simon Arridge, Giuseppe Di Sciacca, Andrea Farina, Pietro Panizza, Elena Venturini, Peter Gordebeke, Pamela Zolda, Paola Taroni

Optical Tomography and Spectroscopy of Tissue XIV

10.1117/12.2576778

Fast-Gated Digital Silicon Photomultiplier Maximizes Light Harvesting and Depth Sensitivity in Time-Domain Diffuse Optics

Alberto Dalla Mora, Laura Di Sieno, Edoardo Ferocino, Enrico Conca, Vincenzo Sesta, Mauro Buttafava, Federica Villa, Franco Zappa, Davide Contini, Alessandro Torricelli, Paola Taroni, Alberto Tosi, and Antonio Pifferi

European Conferences on Biomedical Optics 2021 (ECBO)

https://re.public.polimi.it/handle/11311/1191063

SOLUS: A Novel Multimodal Approach to Diffuse Optics and Ultrasound Imaging of Breast Cancer

Antonio Pifferi, Alberto Dalla Mora, Laura Di Sieno, Giulia Maffeis, Alberto Tosi, Enrico Conca, Vincenzo Sesta, Andrea Giudice, Alessandro Ruggeri, Simone Tisa, Alexander Flocke, Bogdan Rosinski, Jean-Marc Dinten, Mathieu Perriollat, Hélène Sportouche, Christophe Fraschini, Simon Arridge, Giuseppe Di Sciacca, Andrea Farina, Pietro Panizza, Elena Venturini, Peter Gordebeke, Pamela Zolda, and Paola Taroni

European Conferences on Biomedical Optics 2021 (ECBO)

https://re.public.polimi.it/handle/11311/1191062

Wide-area fast-gated single-photon detector with integrated TDC
for near-infrared spectroscopy applications

Conca, Enrico; Sesta, Vincenzo; Villa, Federica Alberta; Buttafava, Mauro; Tisa, Simone; Dalla Mora, Alberto; Contini, Davide; Torricelli, Alessandro; Pifferi, Antonio Giovanni; Di Sieno, Laura; Taroni, Paola; Zappa, Franco; Tosi, Alberto

Proceedings of Single Photon Workshop 2019

http://hdl.handle.net/11311/1156977

A multimodal imaging system hosting an innovative photonic module to improve breast cancer diagnosis: the SOLUS project

Di Sieno, L.; Dalla Mora, A.; Ferocino, E.; Pifferi, A.; Tosi, A.; Conca, E.; Sesta, V.; Giudice, A.; Ruggeri, A.; Tisa, S.; Flocke, A; Rosinski, B.; Dinten, J. -M.; Perriollat, M.; Savery, D.; Sportouche, H.; Arridge, S.; Farina, A.; Panizza, P.; Venturini, E.; Gordebeke, P.; Zolda, P.; Taroni, P.

Proceedings of Single Photon Workshop 2019

http://hdl.handle.net/11311/1156979

Rivelatore a singolo fotone ad area larga con funzionalità di time-gating

Tosi, A.; Villa, F.; Zappa, F.; Torricelli, A.; Dalla Mora, A.; Contini, D.; Pifferi, G.; Taroni, P.; Di Sieno, L.; Buttafava, M.; Conca, E.; Scrofani, G.; Tisa, S.


http://hdl.handle.net/11311/1129437

Bimodal ultrasonic probe comprising an optical device for diagnosis

Taroni, Paola; Tosi, Alberto; Pifferi, Antonio Giovanni; Dalla Mora, Alberto


http://hdl.handle.net/11311/1131488

Wide-area single-photon detector with time-gating capability

Tosi, Alberto; Villa, Federica Alberta; Zappa, Franco; Torricelli, Alessandro; Dalla Mora, Alberto; Contini, Davide; Pifferi, Antonio Giovanni; Taroni, Paola; Di Sieno, Laura; Buttafava, Mauro; Conca, Enrico; Scrofani, Gabriele; Tisa, Simone


http://hdl.handle.net/11311/1170555